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Scry 2, then draw two cards. You lose 2 life.
You draw two cards, lose 2 life, then mill two cards.
Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)
You draw two cards and lose 2 life.
You draw two cards and you lose 2 life.
You draw two cards, lose 2 life, and get (two energy counters).
You draw two cards, lose 2 life, then create a Blood token. (It's an artifact with ", , Discard a card, Sacrifice this token: Draw a card.")
You draw three cards and you lose 3 life.
Draw two cards. Each player loses 2 life.
Casualty 3 (As you cast this spell, you may sacrifice a creature with power 3 or greater. When you do, copy this spell.)
You draw X cards and you lose X life.
Each player loses 2 life. You draw two cards.
Draw four cards. You lose half your life, rounded up.
You draw a card and you lose 1 life.
Amass Orcs 1. (Put a +1/+1 counter on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)
Target player draws two cards and loses 2 life.