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You draw two cards and lose 2 life.
You draw two cards and you lose 2 life.
You draw two cards, lose 2 life, and get (two energy counters).
You draw a card and you lose 1 life.
Amass Orcs 1. (Put a +1/+1 counter on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)
Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)
You draw two cards, lose 2 life, then mill two cards.
Target player draws X cards and loses X life.
Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)
Target player loses 1 life and you gain 1 life.
Draw a card.
Draw four cards. You lose half your life, rounded up.
Target player draws two cards and loses 2 life.
You draw two cards, lose 2 life, then create a Blood token. (It's an artifact with ", , Discard a card, Sacrifice this token: Draw a card.")
You draw two cards and you lose 2 life. Each opponent gets a poison counter.
Draw two cards. Each player loses 2 life.
Target player mills two cards, draws two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)